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Guiquan Chen, Ph.D.
gchen@rics.bwh.harvard.edu
(617)525-5129BIOGRAPHICAL SKETCH
POSITION TITLE: Research Fellow
EDUCATION:
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1994
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Zhejiang
University |
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2004
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The
University of Edinburgh |
PROFESSIONAL EXPERIENCE:
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1994-1996 |
Research assistant, Zhejiang University |
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1996-1998 |
Research assistant, Max-Planck Institute of Neurobiology |
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1999-2004 |
Research assistant, The University of Edinburgh |
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2005- |
Research
Fellow- Center for Neurologic Diseases, Brigham and Women’s Hospital |
HONORS and AWARDS:
1996-1998
Research Fellowship from Max-Planck Society
PUBLICATIONS:
Original Articles
1. Chen G, Kolbeck R, Barde YA, Bonhoeffer T, Kossel A. Relative contribution of endogenous neurotrophins in hippocampal LTP. Journal of Neuroscience 1999; 19: 7983-7990.
2. Chen G, Chen KS, Knox J, Inglis J, Bernard A, Martin SJ, Justice A, McConlogue L, Games D, Freedman SB, Morris RGM. A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimer’s disease. Nature 2000; 408:975-979.
3. Wang J, Chen G, Lu B, Wu C. GDNF acutely potentiates calcium channels and excitatory synaptic transmission in midbrain dopaminergic neurons. NeuroSignals 2003; 12:78-88.
4. Saura CA, Chen G, Malkani S, Choi SY, Kirkwood A, Morris RGM, Shen J. Conditional inactivation of presenilin-1 rescues impaired working memory in a mouse model of Alzheimer’s disease. Journal of Neuroscience 2005; 25: 6734-6744.
Abstracts
1. Morris RGM, Chen G, Chen KS, Inglis J, Knox J, Martin SJ, Justice A, Games D, Freedman SB. Dissociation between age-related and age-independent cognitive deficits in the PDAPP mouse. Euro. J. Neurosci. 2000; 12: 314.
2. Chen G, Bonhoeffer T, Kossel A. Involvement of endogenous BDNF, but not other neurotrophins in hippocampal LTP. Euro. J. Neurosci. 2000; 12: 29.
3. Morris RGM, Chen G, Chen KS, Knox J, Inglis J, Martin SJ, Justice A, Games D, Freedman SB. Dissociation between age-related and age-independent memory deficits in the PDAPP mouse. Society for Neuroscience Abstracts 2000; 26: p.738.
4. Sandin J, Chen G, Martin SJ, Chen KS, Morris RGM. Faster forgetting of spatial memory in the PDAPP mouse-model of Alzheimer s disease. Society for Neuroscience Abstracts 2001; 27: p. 546.4.
5. Chen G, Chen KS, Inglis J, Martin SJ, Freedman SB, Morris RGM. Decrease in CA1 field-potentials correlates with age-related deficit in spatial learning in the PDAPP mouse. Society for Neuroscience Abstracts 2001; 27: p.546.5.
6. Chen G, Wang J, Lu B, Wu C. GDNF acutely potentiates calcium channels and excitatory synaptic transmission in midbrain dopaminergic neurons. Society for Neuroscience Abstracts 2002; 28: p. 751.8
7. Chen G, Saura CA, Malkani S, Choi SY, Kirkwood A, Shen J, Morris RGM. Conditional inactivation of presenilin-1 rescues impaired working memory in a mouse model of Alzheimer’s disease. Society for Neuroscience Abstracts 2003; 29: p. 295.13.
8. Kennedy L, Chen G, Morris RGM, Horsburgh K. Investigating the affect of apolipoprotein E genotype on spatial learning and memory and glucose metabolism in young mice. British Neuroscience Meeting Abstracts 2005; 56.05.