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Tohru Kitada, MD/Ph.D.
tkitada@rics.bwh.harvard.edu
(617)525-5261

BIOGRAPHICAL SKETCH

POSITION TITLE: Research Fellow

EDUCATION:

1990 Niigata University School of Medicine
1999 Juntendo University School of Medicine
   

PROFESSIONAL EXPERIENCE:

1996 - 2001

Visiting fellow in the Department of Molecular Biology, Keio University School of Medicine (includes postdoctoral training, 1999-2001)

1999 - 2002
Research associate in the Department of Neurology, Juntendo University School of Medicine

2002 - 2003
Research associate in the Department of Neurology, Juntendo  University Izu-Nagaoka Hospital

 July 2003 -
Research Fellow in Neurology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA

HONORS and AWARDS:

1999
The Yujin Memorial Award for Excellent Young Scientists, Yujin Society


SELECTED PUBLICATIONS:

  1. Kitada T, Asakawa S, Hattori N, Matsumine H, Yamamura Y, Minoshima S, Yokochi M, Mizuno Y and Shimizu N : Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 392 : 605-608, 1998 
  2. Matsumine H, Yamamura Y, Hattori N, Kobayashi T, Kitada T, Yoritaka A, and Mizuno Y : A microdeletion of D6S305 in a family of autosomal recessive juvenile parkinsonism (PARK2). Genomics 49 : 143-146, 1998
  3. Hattori N, Kitada T, Matsumine H, Asakawa S, Yamamura Y, Yoshino H, Kobayashi T, Yokochi M, Wang M, Yoritaka A, Kondo T, Kuzuhara S, Nakamura S, Minoshima S, Shimizu N and Mizuno Y : Molecular genetic analysis of a novel Parkin gene in Japanese families with AR-JP : evidence for variable homozygous deletions in the Parkin gene in affected individuals. Ann Neurol 44 : 935-941, 1998
  4. Hattori N, Matsumine H, Asakawa S, Kitada T, Yoshino H, Elibol B, Brook AJ, Yamamura Y, Kobayashi T, Wang M, Minoshima S, Shimizu N, and Mizuno Y : Point mutations (Thr240Arg and Ala311Stop) in the parkin gene. Biochem Biophys Res Commun 249 : 754-758, 1998
  5. Shimura H, Hattori N, Kubo S, Yoshikawa M, Kitada T, Matsumine H, Asakawa S, Minoshima S, Yamamura Y, Shimizu N, Mizuno Y : Immunohistochemical and subcellular localization of Parkin protein absence of protein in autosomal recessive juvenile parkinsonism patients. Ann Neurol 45 : 668-672, 1999
  6. Wang M, Hattori N, Matsumine H, Kobayashi T, Yoshino H, Morioka A, Kitada T, Asakawa S, Minoshima S, Shimizu N, Mizuno Y : Polymorphism in the parkin gene in sporadic Parkinson's disease. Ann Neurol 45 : 655-658, 1999
  7. Kitada T, Asakawa S, Matsumine H, Hattori N, Minoshima S, Shimizu N, Mizuno Y : Positional cloning of the autosomal recessive juvenile parkinsonism (AR-JP) gene and its diversity in deletion mutations. Parkinsonism Related Disord 5 : 163-168, 1999
  8. Kitada T, Asakawa S, Matsumine H, Hattori N, Shimura H, Minoshima S, Shimizu N, Mizuno Y : Progress in the clinical and molecular genetics of familial parkinsonism. Neurogenetics 2 : 207-218, 2000
  9. Kitada T, Asakawa S, Minoshima S, Mizuno Y, Shimizu N : Molecular cloning, gene expression, and identification of a splicing variant of mouse parkin gene. Mamm Genome 11 : 417-421, 2000
  10. Wang M, Suzuki T, Kitada T, Asakawa S, Minoshima S, Shimizu N, Tanaka K, Mizuno Y, Hattori N: Developmental changes in the expression of parkin and UbcR7, a parkin-interacting and ubiquitin- conjugating enzyme, in rat brain. J Neurochem 77: 1561-8, 2001

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