Amo T, Sato S, Saiki S, Wolf AM, Toyomizu M, Gautier CA, Shen J, Ohta S, Hattori N. Mitochondrial membrane potential decrease caused by loss of PINK1 is not due to proton leak, but to respiratory chain defects. Neurobiol Dis 2011, 41:111-8.

Martella G, Madeo G, Schirinzi T, Tassone A, Sciamanna G, Spadoni F, Stefani A, Shen J, Pisani A, Bonsi P. Altered profile and D2-dopamine receptor modulation of high voltage-activiated calcium current in striatal medium spiny neurons from animal models of Parkinson’s disease. Neuroscience 2011, 177:240-51.

Nakajima M, Matsuda K, Miyauchi N, Fukunaga Y, Watanabe S, Okuyama S, Pérez J, Fernández-Llebrez P, Shen J, Furukawa Y. Hydrocephalus and abnormal subcommissural organ in mice lacking presenilin-1 in Wnt1 cell lineages. Brain Res 2011, 1382:275-81.

Hakimi M, Selvanantham T, Swinton E, Padmore RF, Tong Y, Kabbach G, Venderova K, Girardin SE, Bulman DE, Scherzer CR, Lavoie MJ, Gris D, Park DS, Angel JB, Shen J, Philpott DJ, Schlossmacher MG. Parkinson’s disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures. J Neural Transm 2011, 118:795-808.

Ho A and Shen J. Presenilins in synaptic function and disease. Trends in Mol Med 2011, 17:617-24.

Billia F, Hauck L, Konecny F, Rao V, Shen J, Mak TW. PTEN-inducible kinase 1 (PINK1)/Park6 is indispensable for normal heart function. Proc Natl Acad Sci USA 2011, 108:9572-7.

Madeo G, Martella G, Schirinzi T, Ponterio G, Shen J, Bonsi P, Pisani A. Aberrant striatal synaptic plastcity in monogenic parkinsonisms. Neuroscience 2011, [Epub August 2].

Tong Y, Giaime E, Yamaguchi H, Ichimura T, Liu Y, Si H, Cai H, Bonventre JV, Shen J. Loss of leucine-rich repeat kinase 2 causes age-dependent bi-phasic alterations of the autophagy pathway. Mol Neurodegener 2012, 7:2.

If you would like to request a PDF of any publications listed here,

please send an email to: aswain4@partners.org.