Shen J., Kelleher RJ 3rd. The presenilin hypothesis of Alzheimer’s disease: Evidence for a loss-of-function pathogenic mechanism. Proc Natl Acad Sci USA 2007, 104:409.

Yamaguchi H and Shen J. Absence of dopaminergic neuronal degeneration and oxidative damage in aged DJ-1-deficient mice. Molecular Neurodegeneration 2007, 2:10.

Kitada T, Pisani A, Porter DR, Yamaguchi H, Tscherter A, Martella G, Bonsi P, Zhang C, Pothos EN, and Shen J. Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice. Proc Natl Acad Sci U S A. 2007, 104:11441-6.

Maraver A., Tadokoro CE, Badura ML, Shen J, Serrano M, and Lafaille JJ. Effect of Presenilins in the apoptosis of thymocytes and homeostasis of CD8+ T cells. Blood 2007, 110:3218-25.

Del Barrio MG, Taveira-Marques R, Muroyama Y, Yuk D, LiS, Wines-Samuelson M, Shen J, Smith HK, Xiang M, Rowitch D, and Richardson WD. A regulatory network involving Foxn4, Mash-1 and Delta-like 4/Notch-1 generates V2a and V2b spinal interneurons from a common progenitor pool. Development 2007, 134:3427-36.

Cookson MR, Dauer W, Dawson T, Fon E, Guo M, Shen J. The roles of kinases in familial Parkinson’s disease. J Neurosci 2007, 27:11865-8.

Yagi T, Giallourakis C, Mohanty S, Scheidig C, Shen J, Zheng H, Xavier RJ, Shaw AC. Defective signal transduction in B lymphocytes lacking presenilin proteins. Proc Natl Acad Sci USA 2008, 105:979-984.

Kim WY and Shen J. Presenilins are required for maintenance of neural stem cells in the developing brain. Molecular Neurodegeneration 2008, 3:2.

Gautier CA, Kitada T, Shen J. Loss of PINK1 Causes Mitochondrial Functional Defects and Increased Sensitivity to Oxidative Stress. Proc Natl Acad Sci USA. 2008, 105:11364-11369.

Shin N, Jeong H, Kwon J, Heo HY, Kwon JJ, Yun HJ, Kim CH, Han BS, Tong Y, Shen J, Hatano T, Hattori N, Kim KS, Chang S, Seol W. LRRK2 regulates synaptic vesicle endocytosis. Exp Cell Res 2008, 314:2055-65.

Hashimoto-Torii K, Torii M, Sarkisian MR, Bartley CM, Shen J, Radtke F, Gridley T, Sestan N, Rakic P. Interaction between Reelin and Notch Signaling Regulates Neuronal Migration in the Cerebral Cortex. Neuron 2008, 60:273-84.

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