Goldberg MS, Pisani A, Haburcak M, Vortherms, TA, Kitada T, Costa C, Tong Y, Martella G, Tscherter A, Martins A, Bernardi G, Roth BL, Pothos EN, Calabresi P and Shen J. Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial parkinsonism-linked gene DJ-1. Neuron 2005, 45:489-96.

Wines-Samuelson ME, Handler M and Shen J. Role of presenilin-1 in cortical lamination and survival of Cajal-Retzius neurons. Dev Biol 2005, 277: 332-346.

Zhang L, Lee J, Song L, Sun X, Shen J, Terracina G, and Parker EM. Characterization of the reconstituted gamma-secretase complex from Sf9 co-expressing presenilin-1, nacastrin, Aph-1a, and pen-2. Biochemistry 2005, 44:4450-4457.

Pardossi-Piquard R, Petit A, Kawarai T, Sunyach C, da Costa CA, Vincent B, Ring S, D'Adamio L, Shen J, Muller U, Hyslop P, Checler F. Presenilin dependent transcriptional control of the Abeta-degrading enzyme neprilysin by intracellular domains of betaAPP and APLP. Neuron 2005, 46:541-554.

Wines-Samuelson M and Shen J. Presenilins in the developing, adult, and aging cerebral cortex. Neuroscientist 2005,11:441-51.

Saura CA, Chen G, Malkani S, Choi S, Takahashi RH, Gouras GK, Kirkwood A, Morris RGM and Shen J. Conditional inactivation of presenelin-1 prevents amyloid accumulation and temporarily rescues associative and working memory impairments in APP transgenic mice. J Neurosci 2005, 20:6755-64.

Sun X, Beglopoulos V, Mattson M and Shen J. Hippocampal memory impairments caused by familial Alzheimer’s disease-linked M146V mutation. Neurodegener Dis 2005, 5:6-15.

Pan Y, Liu Z, Shen J and Kopan R. Notch 1 and 2 cooperate in limb ectoderm to receive an early Jagged2 signal regulating interdigital apoptosis. Dev Biol 2005, 286:472-82.

Grimm MOW, Grimm HS, Patzold AJ, Zinser EG, Halonen R, Duering M, Tschape JA, Muller U, De Strooper B, Shen J, Hartmann T.  Regulation of cholesterol and sphingomyelin metabolism by amyloid-beta and presenilin. Nat Cell Biol 2005, 7:Letter.

Beglopoulos V and Shen J. Regulation of CRE-dependent transcription by presenilins: prospects for therapy of Alzheimer's disease. Trends Pharm Sci 2006, 27:33-40.

Yang X, Tomita T, Wines-Samuelson M, Beglopoulos V, Tansey M,  Kopan R, and Shen J. Notch1 Signaling Influences V2 Interneuron and Motor Neuron Development in the Spinal Cord. Dev Neurosci 2006, 28:102-117.

Pisani A, Martella G, Tscherter A, Costa C, Mercuri NB, Shen J, and Calabresi P. Enhanced sensitivity of DJ-1-deficient dopaminergic neurons to energy metabolism impairment: Role of Na+/K+ ATPase. Neurobiol of Dis 2006, 23:54-60.

Rosen KM, Veereshwarayya V, Moussa CE, Fu Q, Goldberd MS, Schlossmacher MG, Shen J, Querfurth HW. Parkin protects against mitochondrial toxins and beta-amyloid accumulation in skeletal muscle cells. J Biol Chem 2006, 281:12809-16.

Kuo CT, Mirzadeh Z, Sorino-Navarro M, Rasin M, Wang D, Shen J, Sestan N, Garcia-Verdugo J, Alvarez-Buylla A, Jan LY, Jan YN. Postnatal Deletion of Numb/Numblike reveals repair and remodeling capacity in the subventricular neurogenic niche. Cell 2006, 127:1253-64.

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