Goldberg MS, Fleming SM, Palacino JJ, Cepeda C, Lam HA, Bhatnagar A, Meloni EG, Wu N, Ackerson LC, Klapstein GJ, Gajendiran M, Roth BL, Chesselet M, Maidment NT, Levine MS, Shen J. Parkin-Deficient Mice Exhibit Nigrostriatal Deficits but not Loss of Dopaminergic Neurons. J Biol Chem 2003, 278:43628-35.

Yang X, Klein R, Tian X, Cheng H, Kopan R, Shen J. Notch Activation Induces Apoptosis in Neural Progenitor Cells through a p53-Dependent Pathway. Dev Biol 2004, 269:81-94.

Palacino JJ, Sagi D, Goldberg MS, Krauss S, Motz C, Klose J, and Shen J. Mitochondrial Dysfunction and Oxidative Damage in Parkin-Deficient Mice. J Biol Chem 2004, 279:18614-22.

Saura CA, Choi S, Beglopoulos V,  Malkani S, Zhang D, Shankaranarayana Rao BS, Chattarji S, Kelleher III RJ, Kandel ER, Duff K, Kirkwood A, Shen J. Loss of Presenilin Function Causes Impairments of Memory and Synaptic Plasticity Followed by Age-Dependent Neurodegeneration. Neuron 2004, 42: 23-36.*

*See associated minireview in Neuron 2004, 42:189-92.

Shen J, Cookson MR. Mitochondria and Dopamine: New Insights into Recessive Parkinsonism. Neuron 2004, 43:301-4.

Beglopoulos V, Sun X, Saura CA, Lemere CA, Kim RD and Shen J. Reduced B-Amyloid Production and Increased Inflammatory Responses in Presenilin Conditional Knockout Mice. J Biol Chem 2004, 279:46907-14.

Pan Y, Lin M, Tian X, Cheng H, Gridley T, Shen J, Kopan R. γ-Secretase functions through Notch signaling to maintain the lineally related skin appendages but is not required for patterning or their initial morphogenesis. Dev Cell 2004, 7:731-743.

Shen J. Protein kinases linked to the pathogenesis of Parkinson’s disease. Neuron 2004, 44:575-7.

Beglopoulos V and Shen J. Gene-targeting technologies for the study of neurological disorders. Neuromolecular Med 2004, 6:13-30.

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